Have you ever wondered why your mood might affect your eating? Let’s explore one reason why this might be as we evaluate the role of one of the mood regulators, serotonin, to a peptide called enterostatin. Enterostatin is supposed to tell you stop eating (that means it’s anorectic!). But serotonin seems to stop enterostatin. And that means more overeating I’m sorry to say.

Of course serotonin is a fickle friend. It can go up or down. The receptors get changed that mediate serotonin’s effects. So mood can also cause you to stop eating as well!

I’ll bet that you already knew that as you probably ate too much or stopped eating after a painful breakup!

Drugs that affect serotonin levels, such as the class of drugs, selective serotonin reuptake inhibitors (SSRI) often increase eating due to this as well. People who live with depression are most likely to take this drug. So it’s very stressful for someone who is taking these drugs for their depression to then often overeat! This “side effect” of overeating is one of the reasons why the individual might stop taking their medications!

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